Getting Things into Perspective

Likelihood ratios: getting diagnostic testing into perspective.

In modern medicine, sophisticated laboratory tests and imaging studies are often emphasized at the expense of history and physical examination, rather than complementing clinical assessment. Ancillary testing often fails to advance the diagnostic process, and increases patient risk and the expense of medical care. The relative value of clinical evaluation and technological methods is rarely con...

Hypertriglyceridemia Associated With Abdominal Obesity: Getting Contributing Factors Into Perspective.

Getting a Few Things Right and Many Things Wrong

First things first: getting primary care right.

G IVEN THE BROAD AGENDA, HIGH EXPECtations , increasing patient complexity, growing evidence base, intensifying threats to provider work dissatisfaction , and the worsening workforce shortage of primary care physicians, there is an urgent need to fix the problems of primary care. Primary care has been marginalized, and our own professional societies have encountered numerous obstacles in advoca...

Things Are Getting Hairy: Enterobacteria Bacteriophage vB_PcaM_CBB

Enterobacteria phage vB_PcaM_CBB is a "jumbo" phage belonging to the family Myoviridae. It possesses highly atypical whisker-like structures along the length of its contractile tail. It has a broad host range with the capability of infecting species of the genera Erwinia, Pectobacterium, and Cronobacter. With a genome of 355,922 bp, excluding a predicted terminal repeat of 22,456 bp, phage CBB ...